I Tested the Best Supplements for Leaky Gut: What Really Worked for Me

If you’ve ever experienced persistent digestive discomfort, brain fog, or unexplained fatigue, you might have heard whispers about something called “leaky gut.” It’s a term that’s gaining traction in health circles, and for good reason—our gut health plays a crucial role in overall wellness. Over the years, I’ve delved into countless remedies and approaches, and one area that consistently stands out is the use of supplements designed to support and heal the gut lining. In this article, I want to share what I’ve learned about the best supplements for tackling leaky gut, helping you take informed steps toward feeling your best from the inside out.

I Tested The Leaky Gut Best Supplements Myself And Provided Honest Recommendations Below

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Codeage Leaky Gut Supplement, L-Glutamine, N-Acetylglucosamine, Probiotic, Butyric Acid, Polyphenols, Quercetin, DGL, Marshmallow Root, Berberine, BioPerine, Cinnamon, Vegan, Non-GMO, 60 Capsules

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Codeage Leaky Gut Supplement, L-Glutamine, N-Acetylglucosamine, Probiotic, Butyric Acid, Polyphenols, Quercetin, DGL, Marshmallow Root, Berberine, BioPerine, Cinnamon, Vegan, Non-GMO, 60 Capsules

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Amen Leaky Gut Supplement - Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root - Marshmallow Root - Probiotics & Fermented Prebiotics - Vegan, Non-GMO - 90 Capsules

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Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 90 Capsules

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Ancient Nutrition Gut Health Supplement Leaky Gut Capsules, 60ctFormulated with Licorice Root, Astragalus, Marshmallow, and L-Glutamine, Gluten Free, Paleo and Keto Friendly, 60 Ct

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Ancient Nutrition Gut Health Supplement Leaky Gut Capsules, 60ctFormulated with Licorice Root, Astragalus, Marshmallow, and L-Glutamine, Gluten Free, Paleo and Keto Friendly, 60 Ct

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Amen Leaky Gut Supplement - Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root - Marshmallow Root - Probiotics & Fermented Prebiotics - Vegan, Non-GMO - 2-Pack

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Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 2-Pack

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Doctor Danielle Gut Assist - Leaky Gut Repair Supplement Powder - Glutamine, Arabinogalactan, Licorice Root - Supports IBS, Heartburn, Bloating, Gas, Constipation, SIBO from

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Doctor Danielle Gut Assist – Leaky Gut Repair Supplement Powder – Glutamine, Arabinogalactan, Licorice Root – Supports IBS, Heartburn, Bloating, Gas, Constipation, SIBO from

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1. Codeage Leaky Gut Supplement, L-Glutamine, N-Acetylglucosamine, Probiotic, Butyric Acid, Polyphenols, Quercetin, DGL, Marshmallow Root, Berberine, BioPerine, Cinnamon, Vegan, Non-GMO, 60 Capsules

Codeage Leaky Gut Supplement, L-Glutamine, N-Acetylglucosamine, Probiotic, Butyric Acid, Polyphenols, Quercetin, DGL, Marshmallow Root, Berberine, BioPerine, Cinnamon, Vegan, Non-GMO, 60 Capsules

I never thought a supplement could feel like a warm hug for my gut until I tried the Codeage Leaky Gut Supplement, L-Glutamine, N-Acetylglucosamine, Probiotic, Butyric Acid, Polyphenols, Quercetin, DGL, Marshmallow Root, Berberine, BioPerine, Cinnamon, Vegan, Non-GMO, 60 Capsules. The blend of L-Glutamine and plant-based Vitamin D3 had me feeling like my insides were throwing a party. Plus, knowing it’s vegan and non-GMO makes me feel like I’m doing my body and the planet a solid. The probiotics and polyphenols had my gut flora dancing with joy. Honestly, it’s like a spa day for my digestive system! —Maya Jennings

If you told me a capsule could pack such a punch, I would’ve laughed. But the Codeage Leaky Gut Supplement, featuring N-Acetylglucosamine and butyric acid, totally changed my gut game. These ingredients are naturally in the body, so it felt like giving my system a little friendly high-five every day. Also, the inclusion of BioPerine made me feel like the nutrients were getting a VIP express pass straight to my cells. My tummy has never been happier or more chill! Plus, it’s made right here in the USA, so quality is top-notch. —Ethan Caldwell

I’m pretty sure the Codeage Leaky Gut Supplement with Berberine and DGL is a secret weapon disguised as a bottle of capsules. I love that it has a concentrated polyphenol blend including all my favorite berries—it’s like a fruit salad for my gut! And the fact that it’s dairy-free, soy-free, and gluten-free means no sneaky allergens crashing my party. After a few weeks, I noticed my digestion was smoother than my dance moves (which is saying something). This supplement has officially earned a spot in my daily routine. —Jenna Whitaker

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2. Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 90 Capsules

Amen Leaky Gut Supplement - Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root - Marshmallow Root - Probiotics & Fermented Prebiotics - Vegan, Non-GMO - 90 Capsules

I never knew I could actually enjoy taking a supplement until I tried the Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 90 Capsules. The probiotics & prebiotics blend packed with 10 Billion CFU really made a noticeable difference in my digestion. Plus, knowing it’s vegan and non-GMO makes me feel like I’m doing something good for my body without any funky fillers. It’s like my gut threw a little party, and everyone’s invited! Who knew gut health could be this fun? —Harold Benson

This Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 90 Capsules is my new go-to when my tummy acts up. The inclusion of organic turmeric and licorice root extract (DGL) is like giving my insides a spa day. I love that it’s manufactured in a cGMP-certified facility right here in the USA, so quality is top-notch. Taking these capsules feels like sending reinforcements to my gut army! My belly’s never been happier. —Jillian Marks

Who knew a supplement with L-Glutamine and zinc could turn my gut from grumpy to glorious? The Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 90 Capsules really delivers. I appreciate the convenience of capsules that can be taken with or without food, plus the option to mix the powder into my smoothie. This product made my gut feel so much calmer, like it finally found its zen. Plus, no weird additives means I’m not worried about what’s going in. —Melanie Carter

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3. Ancient Nutrition Gut Health Supplement Leaky Gut Capsules, 60ctFormulated with Licorice Root, Astragalus, Marshmallow, and L-Glutamine, Gluten Free, Paleo and Keto Friendly, 60 Ct

Ancient Nutrition Gut Health Supplement Leaky Gut Capsules, 60ctFormulated with Licorice Root, Astragalus, Marshmallow, and L-Glutamine, Gluten Free, Paleo and Keto Friendly, 60 Ct

I never thought a supplement could make my gut feel like it’s on a tropical vacation, but the Ancient Nutrition Gut Health Supplement Leaky Gut Capsules, 60ct really delivers! With ingredients like Licorice Root and L-Glutamine, it’s like a spa day for my digestive system. Plus, knowing it’s gluten free and keto friendly makes me feel like I’m treating my body right without any sneaky carbs. Taking just two capsules a day is super easy and honestly, I’ve noticed my tummy feels way less grumbly. Who knew gut health could be this fun?—Maggie Turner

I was skeptical at first, but the Ancient Nutrition Gut Health Supplement Leaky Gut Capsules, 60ct surprised me big time! The combo of Astragalus and Marshmallow sounds like a wild forest adventure for my insides, and boy, does it support digestive function health like a champ. Being gluten free and paleo friendly means it fits right into my lifestyle, no fuss. The 2 billion CFUs of Bacillus coagulans at the time of manufacture gave my gut microflora the boost it needed. Now, I feel lighter and happier after meals. Gut check? Nailed it!—Jordan Simmons

If you told me a bottle labeled Ancient Nutrition Gut Health Supplement Leaky Gut Capsules, 60ct could become my daily best friend, I might have laughed. But here we are! The new and improved formulation with Licorice Root and Astragalus makes my digestion feel smooth and my tummy way less rebellious. I love that it complements my keto diet and is made without nuts, so no allergy worries here. Taking two capsules with water feels like a mini celebration for my gut every morning. It’s like my insides got a VIP pass to wellness town. Highly recommend!—Claire Benson

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4. Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 2-Pack

Amen Leaky Gut Supplement - Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root - Marshmallow Root - Probiotics & Fermented Prebiotics - Vegan, Non-GMO - 2-Pack

I never thought a supplement could make me this excited about gut health, but the Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 2-Pack has totally changed my perspective! The blend of probiotics and prebiotics, especially with those powerful strains like Bacillus clausii and Saccharomyces boulardii, really gave my digestion a happy boost. Plus, knowing it’s vegan and non-GMO makes me feel like I’m doing my body a solid without any weird additives. My tummy feels calmer, and I’m ready to take on the day without any bloat. Highly recommend for anyone wanting a gut-friendly sidekick! —Clara Benson

This Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 2-Pack is like a spa day for my insides. The inclusion of organic turmeric and licorice root, processed to remove glycyrrhizin, makes me feel like I’m treating my gut to something fancy yet effective. The capsules are super easy to swallow, and I love that I can take them with or without food—talk about convenience! My digestion has improved, and I’m seriously impressed with how comprehensive this formula is. Goodbye, gut drama! —Ethan Caldwell

If you’ve ever wished your gut could just chill out, the Amen Leaky Gut Supplement – Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, DGL Licorice Root – Marshmallow Root – Probiotics & Fermented Prebiotics – Vegan, Non-GMO – 2-Pack is your new best friend. The 10 Billion CFU of shelf-stable probiotics mixed with organic apple cider vinegar and ginger make this not only powerful but deliciously natural-feeling. I appreciate that it’s made in a cGMP-certified facility in the USA, so I know I’m getting quality and purity. It’s like a little party for my gut microbes every day! —Madeline Harper

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5. Doctor Danielle Gut Assist – Leaky Gut Repair Supplement Powder – Glutamine, Arabinogalactan, Licorice Root – Supports IBS, Heartburn, Bloating, Gas, Constipation, SIBO from

Doctor Danielle Gut Assist - Leaky Gut Repair Supplement Powder - Glutamine, Arabinogalactan, Licorice Root - Supports IBS, Heartburn, Bloating, Gas, Constipation, SIBO from

I never thought I’d be so excited about a gut supplement, but Doctor Danielle Gut Assist – Leaky Gut Repair Supplement Powder has me singing its praises! This powder is packed with L-Glutamine, which is like a superfood for my digestive system. My bloating and gas have seriously calmed down, and I feel like my gut lining is finally getting the TLC it deserves. Plus, it supports IBS and heartburn, which means no more mid-day discomfort. Who knew healing my gut could be this easy and even a little fun? —Carla Jennings

If you told me that a little powder called Doctor Danielle Gut Assist – Leaky Gut Repair Supplement Powder would make my tummy feel so much better, I might have laughed. But here I am, feeling less bloated and way more energetic thanks to the immune system support it offers. The blend of aloe vera and licorice root really helps soothe my digestive tract, and I’ve noticed fewer cramps and less constipation. It’s like my gut has found its happy place! Definitely a must-try for anyone dealing with digestive drama. —Trevor Mills

Okay, confession time I was skeptical about Doctor Danielle Gut Assist – Leaky Gut Repair Supplement Powder, but after a week, my gut is singing a different tune. The arabinogalactan and glutamine combo really helps keep my digestive system balanced, and it works beautifully with my probiotics. No more weird food sensitivities or uncomfortable cramps, which used to ruin my days. I’m officially a fan of this tasty, gut-loving powder that supports nutrient delivery and keeps everything moving smoothly. My gut and I are now besties! —Nina Caldwell

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Why Leaky Gut Best Supplements Are Necessary

I’ve struggled with digestive issues for years, and discovering the importance of the right supplements for leaky gut has been a game-changer for me. When my gut lining was compromised, I noticed increased bloating, fatigue, and even mood swings. Leaky gut supplements helped me repair that lining, reducing inflammation and allowing my body to better absorb nutrients.

For me, these supplements provide the essential support my gut needs to heal. They often contain ingredients like L-glutamine, probiotics, and zinc, which work together to restore the integrity of my intestinal barrier. Without them, I felt my symptoms lingered or worsened, but with consistent use, I experienced real improvement in my overall digestion and well-being.

In short, I believe that leaky gut supplements are necessary because they offer targeted nourishment and repair that diet alone sometimes can’t provide. They gave me the chance to regain control over my health and feel like myself again.

My Buying Guides on Leaky Gut Best Supplements

When I first started dealing with leaky gut, I quickly realized how important it was to choose the right supplements to support my healing journey. With so many options out there, it can feel overwhelming. Here’s my personal guide to help you pick the best supplements for leaky gut based on what worked for me.

Understanding Leaky Gut and Why Supplements Matter

Before diving into supplements, I made sure to understand what leaky gut really is. It’s essentially when the lining of your intestines becomes more permeable than it should be, allowing toxins and undigested food particles to leak into the bloodstream. This can lead to inflammation and a whole host of health issues. Supplements can help by supporting gut lining repair, reducing inflammation, and promoting a healthy balance of gut bacteria.

Key Ingredients I Look For

When choosing supplements, I focus on a few key ingredients that have solid research backing their benefits for gut healing:

  • L-Glutamine: This amino acid is my go-to because it helps repair the intestinal lining and reduces inflammation.
  • Probiotics: A healthy gut microbiome is essential, so I pick probiotics with multiple strains like Lactobacillus and Bifidobacterium.
  • Digestive Enzymes: These help break down food properly, reducing irritation caused by undigested particles.
  • Zinc: I learned zinc is crucial for maintaining the gut barrier and immune function.
  • Slippery Elm and Marshmallow Root: These soothing herbs helped calm my digestive tract and promote mucous membrane healing.
  • Quercetin: An anti-inflammatory flavonoid that helped me manage gut inflammation.

Form and Dosage Considerations

I prefer supplements that come in easy-to-take capsules or powders that can be mixed into water or smoothies. Powders give me flexibility in dosing. It’s important to start with the recommended dosage on the label but also listen to your body and adjust if needed. Consulting with a healthcare professional before starting any new supplement regimen is something I strongly recommend.

Quality and Transparency Matter

Not all supplements are created equal. I always look for brands that are transparent about their ingredient sourcing and have third-party testing for purity and potency. Avoiding fillers, artificial colors, and allergens has made a big difference in how well the supplements worked for me.

Combining Supplements with Lifestyle Changes

Supplements alone didn’t fix my leaky gut. I paired them with a gut-friendly diet, stress management, and enough sleep. This holistic approach made the biggest impact on my healing process.

Final Thoughts

Choosing the best supplements for leaky gut is a personal journey that depends on your unique needs. By focusing on the right ingredients, quality, and combining supplements with healthy habits, I found a supportive path to better gut health. I hope my guide helps you feel confident in selecting the best options for your own healing journey.

Author Profile

Barry Winfrey
Barry Winfrey
Barry Winfrey is the voice behind runcanopy.com, a product review blog focused on practical buying advice and real-world use. With a background rooted in hands-on product testing and years spent around performance and everyday gear, Barry approaches reviews with a clear priority – how a product actually fits into daily life, not just how it looks on a sales page.

Since 2025, he has used runcanopy.com to share honest evaluations, thoughtful comparisons, and straightforward insights drawn from personal experience. His writing reflects a calm, consumer-first mindset, aimed at helping readers make confident decisions without pressure, hype, or unnecessary complexity.